> ## Documentation Index
> Fetch the complete documentation index at: https://wuweism.com/llms.txt
> Use this file to discover all available pages before exploring further.

# Hybrid Synthesis

> Surface genuine novelty by reconciling conflicting claims across a literature corpus and company data.

Hybrid Synthesis is designed for one specific problem: finding the gap where existing knowledge fails to agree. Rather than summarizing what is known, it actively searches for conflicts between sources — papers, filings, reports — and builds novel hypotheses in the space where those conflicts live. The approach is inspired by Hong-style recombinant synthesis: take heterogeneous, sometimes contradictory epistemic units and find what emerges when you force them to reconcile.

Navigate to Hybrid Synthesis by selecting **Hybrid Synthesis** in the sidebar, or by opening `/hybrid` directly.

## What Hybrid Synthesis produces

A completed synthesis returns:

* **A structured approach**: the methodological framing for investigating the identified novelty
* **Novel ideas with confidence scores**: candidate hypotheses ranked by how strongly they pass the novelty gate
* **Thesis statements**: falsifiable claims derived from the synthesis, ready to record as governed claims

The top claim from each synthesis run is automatically recorded in your [Claim Ledger](/concepts/claim-ledger).

## Providing sources

Hybrid Synthesis accepts two kinds of inputs: PDF documents and company names. You can use either or both.

<Tabs>
  <Tab title="PDF documents">
    Upload up to **6 PDF files** per synthesis run. These can be journal articles, preprints, reports, or any text-bearing document.

    <Steps>
      <Step title="Click the upload area">
        In the source panel, click **Upload PDFs** or drag your files directly onto the dropzone.
      </Step>

      <Step title="Select up to 6 files">
        Choose your PDF files from your local filesystem. Files are processed in parallel during ingestion.
      </Step>

      <Step title="Confirm the upload list">
        Each uploaded file appears in the source list with its filename. Remove any file by clicking the **×** next to it before running synthesis.
      </Step>
    </Steps>

    Each PDF is run through scientific extraction to identify numeric evidence — figures, measurements, effect sizes, confidence intervals — before synthesis begins. This extraction feeds the novelty gate's evaluation of evidence quality.
  </Tab>

  <Tab title="Company names">
    Enter up to **5 company names** as sources. Wu-Weism retrieves publicly available information associated with each company (filings, publications, announcements) and treats this corpus as additional source material.

    <Steps>
      <Step title="Click Add Company">
        In the source panel, click **Add Company** or type directly into the company name field.
      </Step>

      <Step title="Enter the company name">
        Type the company name exactly as it appears in public records (e.g., "Recursion Pharmaceuticals", "DeepMind"). Press **Enter** to add it.
      </Step>

      <Step title="Add up to 5 companies">
        Repeat for each company. The panel shows your current list and prevents adding more than 5.
      </Step>
    </Steps>

    <Info>
      Company-sourced data is retrieved at synthesis time from public sources. The recency and completeness of that data depends on what is publicly indexed. For proprietary or internal data, upload a PDF export instead.
    </Info>
  </Tab>
</Tabs>

## Research focus (optional)

You can optionally specify a **research focus** — a short phrase or question that guides the synthesis engine toward the region of the source material most relevant to your investigation.

Without a research focus, the synthesis engine explores the full conflict space across all sources. With a focus, it prioritizes conflicts and novelty that bear on your specified question.

Examples of useful research focus inputs:

* "mechanisms linking neuroinflammation to synaptic pruning"
* "causal pathways between ESG disclosure and cost of capital"
* "interventions that reduce antibiotic resistance in hospital settings"

A vague focus (e.g., "anything interesting") is treated the same as no focus. Be specific.

## The synthesis pipeline

Once you start synthesis, Wu-Weism runs a multi-stage pipeline. Progress is shown live in the UI as each stage completes.

```mermaid theme={null}
flowchart LR
    A[ingestion] --> B[pdf_parsing]
    B --> C[entity_harvest]
    C --> D[synthesis]
    D --> E[novelty_gate]
    E -->|pass| F[completed]
    E -->|fail| G[recovery_plan]
    G --> F
```

| Stage            | What happens                                                                                              |
| ---------------- | --------------------------------------------------------------------------------------------------------- |
| `ingestion`      | Sources are received and queued for processing                                                            |
| `pdf_parsing`    | PDFs are parsed; text, structure, and numeric evidence are extracted                                      |
| `entity_harvest` | Named entities, claims, and causal assertions are harvested from all sources                              |
| `synthesis`      | Conflicting claims are identified; recombinant hypothesis generation runs across the conflict space       |
| `novelty_gate`   | The generated hypothesis is evaluated against a novelty criterion (see below)                             |
| `recovery_plan`  | If the novelty gate fails, the system attempts a recovery synthesis targeting a different conflict region |
| `completed`      | Final output is ready                                                                                     |

Progress events stream in real time. You can read intermediate status messages as the pipeline advances.

## The novelty gate

The novelty gate is the quality filter that separates genuine insight from restatement. Before returning output, Wu-Weism evaluates whether the synthesized hypothesis:

1. Is not already explicit in any of the source documents
2. Is not a trivial combination of existing claims
3. Has at least one point of tension with received consensus that it resolves or reframes

If the hypothesis passes, it proceeds directly to `completed`. If it fails, the system enters `recovery_plan` — a second synthesis pass that targets a different conflict region in the corpus. The recovery output is also evaluated by the novelty gate before being returned.

<Note>
  The novelty gate is conservative by design. It is better to return a narrower, well-supported novel claim than a broader, weakly-supported one. A recovery plan result is not a failure — it simply reflects that the first synthesis pass produced something the system judged as insufficiently novel.
</Note>

## Claim recording

After synthesis completes, the highest-confidence novel claim is automatically written to your [Claim Ledger](/concepts/claim-ledger). You can review, annotate, and export it from there.

All other generated claims appear in the synthesis output panel and can be manually added to the Claim Ledger by clicking **Record claim** next to each one.

## Related pages

<CardGroup cols={2}>
  <Card title="PDF Synthesis" icon="file-lines" href="/workbench/pdf-synthesis">
    Single-document causal extraction — a lighter-weight alternative when you have one source.
  </Card>

  <Card title="Claim Ledger" icon="list-check" href="/concepts/claim-ledger">
    Understand how recorded claims are governed, annotated, and exported.
  </Card>

  <Card title="Causal Workbench" icon="message-bot" href="/workbench/causal-chat">
    Use the Causal Workbench to interrogate a synthesized hypothesis with SCM-backed dialogue.
  </Card>

  <Card title="Epistemic Dashboard" icon="chart-mixed" href="/workbench/epistemic-dashboard">
    Track the epistemic quality of your synthesis outputs over time.
  </Card>
</CardGroup>
