Epistemic analysis

The epistemic analysis endpoints surface the knowledge layer beneath Wu-Weism’s causal reasoning: confidence assessment, assumption identification, knowledge-gap detection, and provenance tracking for scientific evidence. Use these endpoints to build epistemic audit trails, expose uncertainty to end users, or retrieve the evidence records underpinning a session’s claims.

All endpoints on this page require authentication. Include your session token in the Authorization header.

Epistemic analysis chat

POST /api/epistemic/chat

Opens an epistemic analysis dialogue. Given a scientific question, the engine assesses the epistemic state of the available evidence: what is known, what is assumed, where the evidence is weak or missing, and how confident Wu-Weism is in its causal inferences. Responses are streamed as Server-Sent Events (SSE).

Request body

string

required

The scientific question or claim you want epistemic analysis on. Can be a hypothesis, a causal claim, or a general research question.Example: "Is there sufficient evidence that chronic cortisol elevation causally reduces hippocampal volume in adult humans?"

string

UUID of an existing session to continue. If omitted, a new session is created.

string

AI provider to use for the analysis: "anthropic", "openai", or "gemini". Defaults to the platform provider if not specified. See Authentication for BYOK key details.

SSE events

The stream emits text chunks and structured events as the analysis progresses.

Event	Payload	Description
`delta`	`{text: string}`	Incremental text of the epistemic analysis narrative.
`confidence`	`{score: number, label: string}`	Overall confidence score (0.0–1.0) and label for the analysed claim.
`assumptions`	`{assumptions: string[]}`	List of causal and epistemic assumptions the analysis rests on.
`gaps`	`{gaps: string[]}`	Knowledge gaps identified — areas where evidence is insufficient.
`done`	`{sessionId: string}`	Emitted when the analysis is complete.
`error`	`{message: string}`	Emitted on fatal error.

Example

curl --request POST \
  --url https://wuweism.com/api/epistemic/chat \
  --header 'Authorization: Bearer <token>' \
  --header 'Content-Type: application/json' \
  --data '{
    "question": "Is there sufficient evidence that chronic cortisol elevation causally reduces hippocampal volume in adult humans?",
    "providerId": "anthropic"
  }'

const response = await fetch('https://wuweism.com/api/epistemic/chat', {
  method: 'POST',
  headers: {
    'Authorization': 'Bearer <token>',
    'Content-Type': 'application/json',
  },
  body: JSON.stringify({
    question: 'Is there sufficient evidence that chronic cortisol elevation causally reduces hippocampal volume in adult humans?',
    providerId: 'anthropic',
  }),
});

const reader = response.body.getReader();
const decoder = new TextDecoder();

while (true) {
  const { done, value } = await reader.read();
  if (done) break;

  const chunk = decoder.decode(value);
  for (const line of chunk.split('\n')) {
    if (line.startsWith('data: ')) {
      const event = JSON.parse(line.slice(6));
      if (event.text) process.stdout.write(event.text);
    }
  }
}

import requests
import json

response = requests.post(
    'https://wuweism.com/api/epistemic/chat',
    headers={'Authorization': 'Bearer <token>'},
    json={
        'question': 'Is there sufficient evidence that chronic cortisol elevation causally reduces hippocampal volume?',
        'providerId': 'anthropic',
    },
    stream=True,
)

for line in response.iter_lines():
    if line.startswith(b'data: '):
        event = json.loads(line[6:])
        if 'text' in event:
            print(event['text'], end='', flush=True)

Retrieve scientific evidence records

GET /api/epistemic/scientific-evidence

Returns scientific evidence records associated with your account. These records are created when PDFs are processed through the hybrid synthesize pipeline or uploaded for epistemic analysis. Each record captures the file’s provenance, a structured summary, and the key scientific findings extracted during analysis.

Response fields

object[]

required

Array of evidence records.

Hide evidence record properties

string

UUID of the evidence record.

string

Original filename of the processed PDF.

string

Structured summary of the document’s scientific content generated during analysis.

object

Origin and processing metadata.

Show provenance properties

string

ID of the synthesis or analysis run that produced this record.

string

Session in which the PDF was processed.

string

ISO 8601 timestamp of when the PDF was analysed.

string[]

List of key scientific findings extracted from the document.

string[]

Variable names and causal entities identified in the document, suitable for use as node names in SCM queries.

Example

curl --request GET \
  --url https://wuweism.com/api/epistemic/scientific-evidence \
  --header 'Authorization: Bearer <token>'

const response = await fetch('https://wuweism.com/api/epistemic/scientific-evidence', {
  headers: { 'Authorization': 'Bearer <token>' },
});

const { evidence } = await response.json();

import requests

response = requests.get(
    'https://wuweism.com/api/epistemic/scientific-evidence',
    headers={'Authorization': 'Bearer <token>'},
)

evidence = response.json()['evidence']

{
  "evidence": [
    {
      "evidenceId": "ev-7c3d1e2f-aa4b-4c9a-b011-d2e3f4a5b678",
      "fileName": "mcewen_2012_stress_hippocampus.pdf",
      "summary": "Comprehensive review of glucocorticoid-mediated structural plasticity in the hippocampus. Covers dendritic remodelling in CA3, BDNF suppression under chronic stress, and reversibility of volume reduction following stress cessation.",
      "provenance": {
        "runId": "run-4e2f9c10-bb3a-4d8e-a917-c1d0f2b3e456",
        "sessionId": "s9f8e7d6-cc4d-4f1a-b802-d6e7f3a0c291",
        "processedAt": "2026-04-05T12:01:08Z"
      },
      "keyFindings": [
        "Chronic stress reduces CA3 dendritic arborisation in rodent models.",
        "Elevated cortisol suppresses BDNF mRNA expression.",
        "Hippocampal volume reduction is partially reversible after stress removal."
      ],
      "causalEntities": [
        "cortisol_level",
        "stress_exposure",
        "BDNF_expression",
        "hippocampal_volume",
        "CA3_dendritic_arborisation"
      ]
    }
  ]
}

Get epistemic session data

GET /api/epistemic/session

Returns epistemic session data for your most recent (or active) session. Use this to retrieve the accumulated epistemic state — questions asked, assumptions surfaced, confidence trajectory, and knowledge gaps identified — across a session’s lifetime.

Response fields

string

required

UUID of the session.

string

required

ISO 8601 timestamp when the session was created.

object[]

required

List of questions asked in this session, in chronological order.

Show question properties

string

UUID of the question.

string

The question text.

number

Confidence score returned for this question (0.0–1.0).

string

Human-readable uncertainty bucket.

string

ISO 8601 timestamp.

string[]

required

Deduplicated list of all causal and epistemic assumptions surfaced across the session.

string[]

required

Deduplicated list of all knowledge gaps identified across the session.

Example

curl --request GET \
  --url https://wuweism.com/api/epistemic/session \
  --header 'Authorization: Bearer <token>'

const response = await fetch('https://wuweism.com/api/epistemic/session', {
  headers: { 'Authorization': 'Bearer <token>' },
});

const session = await response.json();

import requests

response = requests.get(
    'https://wuweism.com/api/epistemic/session',
    headers={'Authorization': 'Bearer <token>'},
)

session = response.json()

{
  "sessionId": "s9f8e7d6-cc4d-4f1a-b802-d6e7f3a0c291",
  "createdAt": "2026-04-05T11:55:00Z",
  "questions": [
    {
      "questionId": "q-001",
      "text": "Is there sufficient evidence that chronic cortisol elevation causally reduces hippocampal volume in adult humans?",
      "confidence": 0.74,
      "uncertaintyLabel": "medium",
      "timestamp": "2026-04-05T11:56:12Z"
    }
  ],
  "aggregateAssumptions": [
    "Rodent models generalise to adult human hippocampal plasticity.",
    "Cortisol as measured in serum is a reliable proxy for tissue-level glucocorticoid exposure.",
    "SUTVA holds: one subject's cortisol exposure does not affect another's hippocampal volume."
  ],
  "aggregateGaps": [
    "Limited longitudinal human data with causal (interventional) designs.",
    "Dose-response relationship between cortisol and hippocampal volume not well characterised in humans.",
    "Mechanistic pathway from cortisol to volume reduction (BDNF vs. neurogenesis vs. dendritic atrophy) not yet resolved."
  ]
}

Overview

Causal Chat

SCM

Claims & Synthesis

Epistemic analysis